G-Protein Coupled Receptors abbreviated as GPCRs refer to a monumental family of cell surface transmembrane proteins dimers required for cell signaling. From external stimuli as well as hormones and neurotransmitters on the one hand, and stimuli of the environment on the other, G-proteins helps to carry out intracellular signaling. This interaction triggers a successive chain of cellular response regarding many other concurrent physiological events such as mood, immune response and sensation. Since GPCRs are involved in a wealth of biological processes in living organisms and constitute the foundation of faith of many biologics and drug in modern and future pharmaceutical and biotechnology industry, the G-Protein Coupled Receptors market has importance.